Blood & Iron · Heart & Circulation · Methylation · Women's Health

5-MTHF 1 mg – 90 servings

Name: 5-MTHF 1 mg
Rating: 4.7 (21 reviews)

✓90-DAY MONEY-BACK GUARANTEE

$26.99$0.29 PER SERVING

Folic acid is not folate. It is a starting material the body has to convert first; this is the finished form, ready to use the moment it arrives. A full 1,700 mcg DFE of Quatrefolic®, a premium branded folate, in one capsule. Ninety to a bottle, three months at one a day.*

Folate in its finished form

Supports normal energy metabolism

Supports red blood cell formation

Supports healthy cell division

Supports normal homocysteine metabolism

A premium branded folate

THIRD-PARTY TESTEDcGMP FACILITYVEGAN CAPSULENON-GMOCOA PER LOTGLUTEN-FREE

How to take

Take 1 capsule daily with food, or as directed by a qualified healthcare professional.. Consistency matters more than timing — pick a moment you'll remember daily.

Consult a healthcare professional before use if pregnant or nursing, taking medication, or if you have a medical condition. Keep out of reach of children.

Quality & testing

Manufactured in the USA in a cGMP-certified facility. Raw materials are tested and qualified before use, and every finished batch is verified by an independent lab for identity, potency, heavy metals, and microbials. Results publish on this page per lot.

Shipping & subscription

Subscribe at any frequency — every month, every 2 months or every 3 months — and save 10%. Subscribe to a second product and every subscription goes to 20%. Free shipping on subscriptions, and you can pause, skip or cancel anytime from your account — no phone calls, no hoops.

What it supports

Folate in its finished form

Folic acid is a starting material the body has to convert first. This is the form that arrives ready to use.

Supports normal energy metabolism

Folate is a cofactor in the everyday cellular work that turns food into usable energy.

Supports red blood cell formation

Your body makes new red blood cells constantly, and folate is one of the nutrients that job depends on.

Supports healthy cell division

Folate is required for DNA synthesis, which is why it matters most in tissues that renew quickly.

Supports normal homocysteine metabolism

Folate is part of the pathway the body uses to keep homocysteine within its normal range.

A premium branded folate

Quatrefolic®, with the exact amount printed on the label and no proprietary blend.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Folate, in its finished form.

Quatrefolic® L-5-MTHF — 1,700 mcg DFE folate per capsule

	Quatrefolic® 1,700 mcg DFE	Folic acid supplements	Folate in a multivitamin
Premium branded folate	●	—	Varies
The finished form, not a precursor	●	—	Varies
A full dose in one capsule	●	Varies	—
Exact amount disclosed	●	●	Varies
No proprietary blend	●	Varies	—
COA published every lot	●	—	—

GENERAL FORM COMPARISON — INDIVIDUAL PRODUCTS VARY BY BRAND

What's happening
while you wait.

*INDIVIDUAL RESULTS VARY. THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA.

Inside the formula

Quatrefolic® L-5-MTHF — 1,700 mcg DFE folate per capsule

Folic acid and folate get talked about as if they are the same thing. They are not. Folic acid is a starting material, and the body converts it through several steps before a cell can use it. L-5-MTHF is the finished form and skips that conversion entirely. That is what is in this capsule: Quatrefolic®, a premium branded folate chosen because it arrives ready to use, at an amount meant to do something rather than tick a box.

CUSTOMER REVIEWS

4.7 /5 ★

Based on 21 reviews

95%

Would recommend this supplement

Customers say

✦ Summarised from customer reviews.

The most common theme is dose choice: many reviewers say they specifically wanted 1 mg rather than a higher-strength methylfolate, describing it as a more practical everyday amount and easier to tolerate. Capsule size and the absence of aftertaste come up repeatedly, as does the simplicity of the formula — several mention preferring methylfolate on its own rather than inside a large vitamin blend. Critical reviews focus on judging results rather than on side effects, with several reviewers saying it is too early to tell after a few weeks.

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Frequently asked
questions

How do I know what's on the label is in the bottle?

Trust should be verifiable. Every batch we produce is tested by an independent laboratory, and the certificate of analysis for your exact lot is published on this page — potency, heavy metals, microbials. Testing begins the moment a raw material arrives, continues through production, and no batch is released until every result clears. The label is a claim. The COA is the proof.

How do you choose your ingredients and doses?

We formulate from peer-reviewed clinical research and dose to match it. We select the highest-grade material available for each ingredient, in the form the body absorbs best, and where a patented or branded form is the one that has actually been studied, that is the one we use. Every active appears at its exact amount, with no proprietary blends and nothing added that doesn't need to be there.

Where are CoreLabs supplements made?

In our own cGMP-certified facility in California's Central Valley. Manufacturing in-house means quality is our responsibility at every step rather than a supplier's promise. Raw materials are purchased through established US suppliers who import and qualify them, and every material is tested against our own specification before it enters production — wherever it originated.

Why are CoreLabs supplements more expensive?

Because of what goes in. We buy the highest grade of each raw material, in the most absorbable form, and we work with the branded and patented ingredient houses whose material the clinical research was actually run on — names like Lonza, Albion, RIBUS, Sabinsa and Indena. Wherever possible those materials are made domestically. Our capsules are titanium-dioxide free. Then it is made in our own facility and third-party tested batch by batch. Every one of those choices costs more than the alternative, and the price reflects it. Anyone can claim quality — we publish ours.

How is this different from folic acid?

Folic acid is a starting material — the body converts it through several steps before a cell can use it. L-5-MTHF is the finished form, so it arrives ready to use without that conversion.

What is Quatrefolic®?

A premium branded folate from Gnosis, and we use it because with this nutrient the quality of the ingredient counts as much as the amount. Every lot is tested and the certificate published.

Can I take it with other supplements?

Yes, with one check first. Many multivitamins and prenatals already contain folate, and there is no reason to stack several sources.

Should I speak to a professional first?

If you are pregnant, planning to be, or taking any medication, yes. Folate is one of the nutrients most worth getting personal advice on rather than guessing.

How long does a bottle last?

Ninety capsules at one a day is three months.