Quatrefolic® Methylfolate

Quatrefolic® is a patented glucosamine salt of (6S)-5-methyltetrahydrofolate — the biologically active form of folate your cells actually use.

Why not folic acid?

Synthetic folic acid must be converted through several enzymatic steps before the body can use it — and a large share of the population carries MTHFR gene variants that slow this conversion dramatically. Methylfolate skips the bottleneck entirely, arriving already active.*

Why we chose it

Quatrefolic® offers superior solubility and bioavailability compared to older calcium-salt methylfolate forms, backed by its own pharmacokinetic research.*

Where you'll find it

In Active B-Complex (CL-201), alongside methylcobalamin B12 and the full family of body-ready B vitamins.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.